Metabolomix+
The only nutritional testing of its kind – combines several methodologies and biomarkers and synthesizes the results. Metabolomix+ is similar to our comprehensive NutrEval with the advantage of being collected entirely at home.
Dynamic reporting allows for easy interpretation and clinically actionable results.
Metabolomix+: A Non-Invasive Personalized Nutritional Assessment
The Metabolomix+ is a unique combination of nutritional tests that provides an analysis of key nutritional biomarkers. A first morning void (FMV) urine collection, with optional add-on bloodspot finger stick and buccal swab, the Metabolomix+ nutritional test is a non-invasive, patient-friendly way to assess the functional need for antioxidants, B-vitamins, minerals, digestive support, fatty acids, and amino acids. Insights gained from the Metabolomix+ nutritional test allows clinicians to target nutritional therapies to meet the precise needs of their patients.
Which patients might benefit from functional nutritional testing?
Common clinical indications for testing include:
Several diseases are associated with abnormal organic acid, amino acid, and fatty acid levels such as depression, anxiety, cardiovascular disease, neurocognitive decline, diabetes, cancer, anorexia, and many others.7,8,9,10
*Testing is not performed in patients under 2 years old.
About the Metabolomix+ Profile
The Metabolomix+ Profile report categorizes results into several metabolic areas (see sample report for individual analytes):
- Personalized Results Overview and Nutrient Need Overview
- Functional Imbalance Scores in areas of methylation, toxic exposure, mitochondrial dysfunction, fatty acid imbalances, and oxidative stress
- Nutrient Need Overview with recommendations for antioxidants, B-vitamins, minerals, essential fatty acids, GI support, and amino acids
- Interpretation-At-A-Glance pages provide nutritional educational support for you and your patient highlighting the function of each nutrient, cause of deficiency, complications of deficiency and food sources of the nutrient
- Organic Acids (urine)
- Malabsorption and Bacterial/ Yeast Dysbiosis Markers are metabolites produced by the gastrointestinal microbiome
- Cellular Energy & Mitochondrial Metabolites are biomarkers of carbohydrate and fatty acid metabolism, and the citric acid (Kreb’s) cycle
- Neurotransmitter Metabolites are downstream byproducts of epinephrine, norepinephrine, serotonin and dopamine
- Vitamin Markers are specific analytes used to assess functional levels of vitamin cofactors
- Toxin & Detoxification Markers relate to certain toxic metabolites and the body’s detoxification capacity
- Oxalate Markers relate to kidney stone formation, oxidative stress and metabolic dysfunction
- Amino Acids (urine)
- Essential Amino Acids must be derived from dietary sources
- Nonessential Amino Acids are synthesized by the body
- Intermediary Metabolites are byproducts of amino acid metabolism
- B Vitamin Markers are involved in biochemical reactions that specifically require B vitamins
- Urea Cycle Markers are byproducts associated with nitrogen (ammonia) detoxification
- Glycine/Serine Metabolites are involved in the serine-to-choline pathway and the methylation pathways
- Dietary Peptide Related Markers can indicate incomplete protein breakdown and meat intake
- Oxidative Stress Markers (urine) include the oxidative damage markers lipid peroxides and 8-OHdG
+ COMPONENTS
- Add-on Essential and Metabolic Fatty Acids Markers (Bloodspot- whole blood)
- Omega 3 Fatty Acids are essential for brain function and cardiovascular health and are anti-inflammatory
- Omega 6 Fatty Acids are involved in the balance of inflammation
- Omega 9 Fatty Acids are important for brain growth, nerve cell myelin, and reducing inflammation
- Saturated Fatty Acids are involved in liproprotein metabolism and adipose tissue inflammation
- Monounsaturated Fats include omega 7 fats and unhealthy trans fats
- Delta-6 Desaturase Activity assesses efficiency of this enzyme to metabolize omega 6’s and omega 3’s
- Cardiovascular Risk includes specific ratios and the Omega 3 Index
- Add-on Comprehensive Urine Element Profile (urine) assesses 20 toxic and 15 mineral elements
- Add-on SNPs (buccal swab) include MTHFR, COMT, TNF-a, and APOE
